9i传媒有限公司

康乐讲席教授

讲席教授

邮箱:濒办补苍驳蔼颈辞锄.补肠.肠苍;濒办补苍驳蔼蝉耻补迟-蝉锄.别诲耻.肠苍

所在单位:生物科学系

个人介绍

康乐,中国科学院院士,美国国家科学院外籍院士,欧洲分子生物学组织外籍院士,中国科学院特聘研究员,9i传媒有限公司合成生物学院讲席教授,国际着名生态基因组学家。1990年在中国科学院获得博士学位后,在中国科学院动物研究所从事科学研究,主要开展生态基因组学研究。

所获荣誉

1.2011年,何梁何利生命科学与技术进步奖

2.2013年,美国昆虫学会颁发的杰出科学家奖

3.2015年, “谈家桢生命科学奖”成就奖

4.2017年,国家自然科学二等奖

5.2017年,中国科学院杰出成就奖

6.2019年,“马世骏生态科学成就奖”

7.2021年,国际化学生态学会西弗斯坦-西蒙尼奖

8.2022年,全国创新争先奖

9.2023年,李佩教学名师奖

Major Publications (代表文章)

1.Guo, X.J., Gao, L., Li, S.W., Gao, J., Wang, Lv, J., Wei, J.Y., Yang, J., Ke, H., Ding, Q., Yang, J., Guo, F.S., Zhang, H.W., Lei, X.G., and Kang*, L., 2025. Decoding 4-vinylanisole biosynthesis and pivotal enzymes in locusts.Nature,(25 June, 2025). https://doi.org/10.1038/s41586-025-09110-y

2.Li, X., Jiang, F., Liu, Q., Zhang, Z., Fang, W.J., Wang, Y.T., Liu, H.R., Kang*, L., 2025. GAF-dependent chromatin plasticity determines promoter usage to mediate locust gregarious behavior.The EMBO Journal44(10): 2928-2948.

3.Liu, Q., Jiang, F., Li, R., Liu, S.L., Fang, W.J., Li, X., Hu, T., Feng, L., Zhang, J., Liu, Z.K., He, J., Guo, W., Wang, X.H., Sun, Z.Y., Li, J.J., Gao, Y.N., Yi J.C., Li, Q.Y., Wang, X.X., Wei, L.Y., Kang*, L., 2025, Chromatin dynamics of a large-sized genome provides insights into polyphenism and X0 dosage compensation of locusts.Nature Genetics, DOI : 10.1038/s41588-025-02330-y.

4.Li, J., Li, J.J., Cao, L.L., Chen, Q.H., Ding*, D., and Kang*, L. 2024. An iron-binding protein of entomopathogenic fungus suppresses the proliferation of host symbiotic bacteria.Microbiome,12:202

5.ang, J., He, H., Dong, S.J., Lv, J., Cheng, L.L., Yu, Q.Q., Kang*, L., Guo, X.J. 2025, Locusts adopt IP3 as a second messenger for olfactory signal transduction. Science Advances. DOI: 10.1126/sciadv.ads1352.

6.Kang, X.L., Yang, M.L., Cui, X.S., Wang, H.M., Kang, L., 2023. Spatially differential regulation of ATF2 phosphorylation contributes to warning coloration of gregarious locusts.Science Advances, 9: eadi5168.

7.Guo, S.Y., Hou, L., Dong, L.S., Nie, X., Kang, L., Wang, X.H., 2023. PLIN2-induced ectopic lipid accumulation promotes muscle aging in gregarious locusts.Nature Ecology & Evolution, 7(6): 914–925.

8.Liu, Q., Cui, F., Liu, X., Fu, Y., Fang, W., Kang, X., et al., 2023. Association of virome dynamics with mosquito species and environmental factors.Microbiome, 11(1): 101.

9.Guo, X.J., Yu, Q.Q., Chen, D.F., Wei, J.N., Yang, P.C., Yu, J., Wang, X.H., Kang, L., 2020. 4-Vinylanisole is an aggregation pheromone in locusts.Nature, 584(7822): 584–588.

10.Chang, H.T., Cassau, S., Krieger, J., et al., 2023. A chemical defense deters cannibalism in migratory locusts.Science, 380: 537–542.

11.He, J., Zhu, Y.N., Wang, B.C., Yang, P.C., Guo, W., Liang, B., Jiang, F., Wang, H.M., Wei, Y.Y., Kang, L. 2022. piRNA-guided intron removal from pre-mRNAs regulates density-dependent reproductive strategy.Cell Reports, 39(4): 110593.

12.Wei, J.N., Shao, W.B., Cao, M.M., Ge, J., Yang, P.C., Chen, L., Wang, X.H., Kang, L., 2019. Phenylacetonitrile in locusts facilitates an antipredator defense by acting as an olfactory aposematic signal and cyanide precursor.Science Advances, 4: DOI: 10.1126/sciadv.aav5495.

13.Du, B.Z., Ding, D., Ma, C., Guo, W., Kang, L., 2021, Locust density shapes energy metabolism and oxidative stress resulting in divergence of flight traits.Proceedings of the National Academy of Sciences of USA, 119(1): e2115753118, DOI: 10.1073/pnas.2115753118.

14.Wang, YD., Tong, X.W., Yuan, S.L., Yang, P.C., Li, L., Zhao, Y., Kang, L., 2022. Variation of TNF modulates

cellular immunity of gregarious and solitary locusts against fungal pathogenMetarhiziumAnisopliae. Proceedings of the National Academy of Sciences of USA, 119, doi:10.1073/pnas.2120835119.

15.Wang, X.H., Fang, X.D., Yang, P.C.,……., and Kang, L. 2014. The locust genome provides insight into swarm formation and long-distance flight.Nature Communication, 5: 2957.

16.He, J., Chen, Q.Q., Wei, Y.Y., Jiang, F., Yang, M.L., Hao, S.G., Guo, X.J., Chen, D.H., and Kang, L. 2016. MicroRNA-276 promotes egg-hatching synchrony by up-regulatingbrmin locusts.Proceedings of the National Academy of Sciences of USA, 113: 584-589.

17.Wu, R., Wu, Z.M., Wang, X.H., Yang, P.C., Yu, D., Zhao, C.X., Xu, G.W., and Kang, L. 2012. Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts.Proceedings of the National Academy of Sciences of USA, 109: 3259-3263.

18.Ma, Z.Y., Guo, W., Guo, X.J., Wang, X.H. and Kang, L. 2011. Modulation of behavioral phase changes of the migratory locust by the catecholamine metabolic pathway.Proceedings of the National Academy of Sciences of USA, 108: 3882-3887.

19.Wei, Y.Y., Chen, S., Yang, P.C., Ma, Z.Y., Kang, L., 2009. Characterization and comparative profiling of the small RNA transcriptomes in two phases of locust.Genome Biology,10: R6.

20.Cease, A.J., Elser, J.J., Ford, C.F., Hao, S.G., Kang, L., and Harrison, J.F. 2012. Heavy livestock grazing promotes locust outbreaks by lowering plant nitrogen content.Science, 335: 467-469.

研究领域

1. 真菌杀虫剂的开发与创制。通过合成生物学和基因改造技术开发新型真菌杀虫剂以及相关生产工艺。